Interaction of Polysialic Acid with CCL21 Regulates the Migratory Capacity of Human Dendritic Cells
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چکیده
منابع مشابه
Interaction of Polysialic Acid with CCL21 Regulates the Migratory Capacity of Human Dendritic Cells
Dendritic cells (DCs) are the most potent antigen-presenting cells (APCs). Immature DCs (iDCs) are situated in the periphery where they capture pathogen. Subsequently, they migrate as mature DCs (mDCs) to draining lymph nodes to activate T cells. CCR7 and CCL21 contribute to the migratory capacity of the DC, but it is not completely understood what molecular requirements are involved. Here we d...
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ژورنال
عنوان ژورنال: PLoS ONE
سال: 2009
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0006987